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Iodine Software Expands Executive Team with New Chief Commercial Officer to Scale Clinical Intelligence AI Platform for Health Systems

Following $2.1B in recovered reimbursement in 2024, Iodine strengthens its leadership to meet growing demand for AI solutions that drive proven financial impact.

Iodine Software, the leading AI-powered revenue cycle company, today announced the appointment of Valerie Mondelli, RPh, MBA, as Chief Commercial Officer (CCO). Mondelli joins the company’s executive leadership team at a pivotal time, as Iodine prepares to scale its impact following a landmark year in which it helped health systems recover more than $2.1 billion in reimbursement in 2024.

With more health systems under increasing financial strain and AI adoption on the rise, Iodine is one of the few healthcare AI companies delivering clear, quantifiable results. A recent McKinsey report noted that only 23% of healthcare executives said their AI vendors demonstrated positive ROI. In contrast, Iodine partners routinely recover millions in right-sized reimbursement, reduce denials, and streamline revenue cycle operations.

“As the healthcare market becomes more crowded with AI vendors, health systems need partners who don’t just promise impact—but prove it,” said William Chan, CEO and Co-Founder of Iodine Software. “Valerie brings decades of commercial leadership and a deep understanding of healthcare’s financial pressures. Her experience and customer-first mindset will help us align our teams and scale our growth strategy for even greater impact.”

Mondelli brings more than 25 years of commercial leadership experience across healthcare, retail pharmacy, payers, pharmaceutical manufacturers, and health IT. Most recently, she served as Chief Commercial Officer at RevSpring, where she led its transformation into a digital engagement and payments platform. Her experience spans companies like Eli Lilly, RelayHealth (McKesson), and FiServ, and in 2023, she was named one of Drug Store News' Top Women in Business.

“Hospitals are under immense pressure—grappling with rising denials, financial strain, and mounting complexity,” said Valerie Mondelli, Chief Commercial Officer of Iodine Software. “What sets Iodine apart is its ability to turn deep clinical intelligence into financial impact. By helping health systems recover earned revenue and prevent denials, we’re not just improving margins—we’re reinforcing their ability to deliver on their care mission. I’m proud to join a team so committed to solving healthcare’s hardest problems.”

Hundreds of hospitals and health systems trust CognitiveML™—Iodine’s proprietary Clinical Intelligence AI engine—purpose-built for healthcare’s complexity. By mirroring clinical judgment and leveraging one of the nation’s largest inpatient datasets, CognitiveML™ delivers the most complete picture of patient care. It uncovers hidden revenue by ensuring accurate documentation and coding—driving measurable financial and improved quality outcomes:

  • 63% reduction in medical review time (from 15 to 5 minutes)
  • $15M annualized impact through accurate level-of-care adjustments
  • 139% increase in incremental financial return per facility, averaging $1.5M

About Iodine Software

Iodine Software is the leader in AI-powered clinical intelligence, helping healthcare organizations capture the full value of patient care. Our solutions drive accurate documentation, optimize reimbursement, reduce administrative burden, and help prevent costly denials—powering more efficient revenue cycle operations. For over a decade, health systems have trusted Iodine to apply the right AI—whether machine learning, deep learning, GenAI and Agentic AI— to the right use case, consistently delivering reliable, high-impact outcomes.

Iodine’s proprietary Clinical Intelligence Engine, CognitiveML, mirrors clinical judgment and draws insights from one of the largest sets of inpatient clinical data in the country. The platform continuously reviews every patient chart to deliver the most holistic, real-time clinical snapshot available. Recognized as Best in KLAS, Iodine’s Clinical Intelligence Suite scales clinical intelligence through solutions like AwareCDI, AwareUM, and AwarePre-Bill, helping healthcare organizations achieve financial returns and improve quality. Learn more at www.iodinesoftware.com.

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