UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F COVER PAGE Report for the Calendar Year or Quarter Ended: March 31, 2013 Check here if Amendment [ ]; Amendment Number: This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name:GENERAL AMERICAN INVESTORS COMPANY, INC. Address: 100 PARK AVE 35TH FLOOR NEW YORK, NY 10017 13F File Number: 28-461 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Eugene S. Stark Title: Vice-President, Administration Phone: 212-916-8447 Signature, Place, and Date of Signing: Eugene S. Stark New York, NY April 30, 2013 Report Type (Check only one.): [X] 13F HOLDINGS REPORT. [ ] 13F NOTICE. [ ] 13F COMBINATION REPORT. List of Other Managers Reporting for this Manager: Form 13F File Number Name I AM SIGNING THIS REPORT AS REQUIRED BY THE SECURITIES EXCHANGE ACT OF 1934. FORM 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 Form 13F Information Table Entry Total: 52 Form 13F Information Table Value Total: $1,054,970 FORM 13F INFORMATION TABLE VALUE SHARES/ SH/ PUT/ INVSTMT OTHER VOTING AUTHORITY NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DSCRETN MANAGERS SOLE SHARED NONE ------------------------------ ---------------- --------- -------- -------- --- ---- ------- ------------ -------- -------- -------- ABB Ltd. ADR COM 000375204 27312 1200000 SH Sole 1200000 Adams Express COM 006212104 1726 147059 SH Sole 147059 Alpha Natural Resources, Inc. COM 02076X102 6716 818069 SH Sole 818069 American Express Company COM 025816109 21250 315000 SH Sole 315000 Aon plc COM G0408V102 20325 330492 SH Sole 330492 Apache Corporation COM 037411105 25577 331478 SH Sole 331478 Apple Inc. COM 037833100 29658 67000 SH Sole 67000 Arch Capital Group Ltd. COM G0450A105 43370 825000 SH Sole 825000 Ariad Pharmaceuticals, Inc. COM 04033A100 4791 265000 SH Sole 265000 ASML Holding N.V. COM N07059210 21203 311850 SH Sole 311850 Berkshire Hathaway Inc. Class COM 084670108 17191 110 SH Sole 110 Cameco Corporation COM 13321L108 8505 409308 SH Sole 409308 Canadian Natural Resources Lim COM 136385101 9639 300000 SH Sole 300000 Celgene Corporation COM 151020104 13909 120000 SH Sole 120000 Cisco Systems, Inc. COM 17275R102 20059 960000 SH Sole 960000 Costco Wholesale Corporation COM 22160K105 41860 394500 SH Sole 394500 Cytokinetics, Incorporated COM 23282W100 900 789211 SH Sole 789211 Diageo plc ADR COM 25243Q205 44044 350000 SH Sole 350000 EMC Corporation COM 268648102 14692 615000 SH Sole 615000 Everest Re Group, Ltd. COM G3223R108 31166 240000 SH Sole 240000 Ford Motor Company COM 345370860 16622 1264063 SH Sole 1264063 Gilead Sciences, Inc. COM 375558103 20976 428600 SH Sole 428600 Halliburton Company COM 406216101 29297 725000 SH Sole 725000 Idenix Pharmaceuticals, Inc. COM 45166R204 3041 858979 SH Sole 858979 International Game Technology COM 459902102 12375 750000 SH Sole 750000 JPMorgan Chase & Co. COM 46625H100 22544 475000 SH Sole 475000 Kohl's Corporation COM 500255104 13103 284050 SH Sole 284050 M&T Bank Corporation COM 55261F104 11348 110000 SH Sole 110000 MetLife, Inc. COM 59156R108 15208 400000 SH Sole 400000 Microsoft Corporation COM 594918104 22741 795000 SH Sole 795000 Nelnet, Inc. COM 64031N108 19858 587500 SH Sole 587500 Nucor Corporation COM 670346105 4615 100000 SH Sole 100000 Occidental Petroleum Corporati COM 674599105 9404 120000 SH Sole 120000 Owens Corning COM 690742101 14195 360000 SH Sole 360000 PartnerRe Ltd. COM G6852T105 24209 260000 SH Sole 260000 PepsiCo, Inc. COM 713448108 18986 240000 SH Sole 240000 Pfizer Inc. COM 717081103 21813 755808 SH Sole 755808 Platinum Underwriters Holdings COM G7127P100 22324 400000 SH Sole 400000 QUALCOMM Incorporated COM 747525103 46858 700000 SH Sole 700000 Republic Services, Inc. COM 760759100 35874 1087100 SH Sole 1087100 Royce Value Trust, Inc. COM 780910105 2498 165898 SH Sole 165898 Target Corporation COM 87612E106 31487 460000 SH Sole 460000 The ADT Corporation COM 00101J106 14315 292500 SH Sole 292500 The Dow Chemical Company COM 260543103 8858 278200 SH Sole 278200 The TJX Companies, Inc. COM 872540109 72213 1544668 SH Sole 1544668 Towers Watson & Co. Class A COM 891894107 18300 263998 SH Sole 263998 Ultra Petroleum Corp. COM 903914109 12563 625000 SH Sole 625000 United Technologies Corporatio COM 913017109 28029 300000 SH Sole 300000 Visteon Corporation COM 92839U206 19053 330211 SH Sole 330211 Vodafone Group plc ADR COM 92857W209 14856 523100 SH Sole 523100 Waste Management, Inc. COM 94106L109 18625 475000 SH Sole 475000 Weatherford International Ltd. COM H27013103 24887 2050000 SH Sole 2050000