UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F COVER PAGE Report for the Calendar Year or Quarter Ended: December 31, 2012 Check here if Amendment [ ]; Amendment Number: This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name:GENERAL AMERICAN INVESTORS COMPANY, INC. Address: 100 PARK AVE 35TH FLOOR NEW YORK, NY 10017 13F File Number: 28-461 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Eugene S. Stark Title: Vice-President, Administration Phone: 212-916-8447 Signature, Place, and Date of Signing: Eugene S. Stark New York, NY February 07, 2013 Report Type (Check only one.): [X] 13F HOLDINGS REPORT. [ ] 13F NOTICE. [ ] 13F COMBINATION REPORT. List of Other Managers Reporting for this Manager: Form 13F File Number Name I AM SIGNING THIS REPORT AS REQUIRED BY THE SECURITIES EXCHANGE ACT OF 1934. FORM 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 Form 13F Information Table Entry Total: 54 Form 13F Information Table Value Total: $975,101,000 List of Other Included Managers: No. 13F File Number Name FORM 13F INFORMATION TABLE VALUE SHARES/ SH/ PUT/ INVSTMT OTHER VOTING AUTHORITY NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DSCRETN MANAGERS SOLE SHARED NONE ------------------------------ ---------------- --------- -------- -------- --- ---- ------- ------------ -------- -------- -------- ABB Ltd. ADR COM 000375204 24948 1200000 SH Sole 1200000 Adams Express COM 006212104 1557 147059 SH Sole 147059 Alpha Natural Resources, Inc. COM 02076X102 4140 425000 SH Sole 425000 American Express Company COM 025816109 18106 315000 SH Sole 315000 Aon plc COM G0408V102 18379 330492 SH Sole 330492 Apache Corporation COM 037411105 26021 331478 SH Sole 331478 Apple Inc. COM 037833100 35656 67000 SH Sole 67000 Arch Capital Group Ltd. COM G0450A105 36317 825000 SH Sole 825000 Ariad Pharmaceuticals, Inc. COM 04033A100 4028 210000 SH Sole 210000 ASML Holding N.V. COM N07059210 20080 311850 SH Sole 311850 Berkshire Hathaway Inc. Class COM 084670108 14747 110 SH Sole 110 Canadian Natural Resources Lim COM 136385101 8661 300000 SH Sole 300000 Celgene Corporation COM 151020104 11771 150000 SH Sole 150000 Cisco Systems, Inc. COM 17275R102 18863 960000 SH Sole 960000 Costco Wholesale Corporation COM 22160K105 38949 394500 SH Sole 394500 Cytokinetics, Incorporated COM 23282W100 463 702111 SH Sole 702111 Diageo plc ADR COM 25243Q205 40803 350000 SH Sole 350000 EMC Corporation COM 268648102 10879 430000 SH Sole 430000 Epoch Holding Corporation COM 29428R103 25460 912562 SH Sole 912562 EverBank Financial Corp. COM 29977G102 1938 130000 SH Sole 130000 Everest Re Group, Ltd. COM G3223R108 26388 240000 SH Sole 240000 Ford Motor Company COM 345370860 16370 1264063 SH Sole 1264063 Gilead Sciences, Inc. COM 375558103 15740 214300 SH Sole 214300 Halliburton Company COM 406216101 26018 750000 SH Sole 750000 Idenix Pharmaceuticals, Inc. COM 45166R204 1797 370414 SH Sole 370414 International Game Technology COM 459902102 10628 750000 SH Sole 750000 JPMorgan Chase & Co. COM 46625H100 21985 500000 SH Sole 500000 JPMorgan Chase & Co. Call Warr COM 46634E114 2669 225000 SH Sole 225000 Kohl's Corporation COM 500255104 12208 284050 SH Sole 284050 M&T Bank Corporation COM 55261F104 10832 110000 SH Sole 110000 MetLife, Inc. COM 59156R108 13176 400000 SH Sole 400000 Microsoft Corporation COM 594918104 21234 795000 SH Sole 795000 Nelnet, Inc. COM 64031N108 19959 670000 SH Sole 670000 Nucor Corporation COM 670346105 8632 200000 SH Sole 200000 Occidental Petroleum Corporati COM 674599105 7661 100000 SH Sole 100000 Owens Corning COM 690742101 13316 360000 SH Sole 360000 PartnerRe Ltd. COM G6852T105 20927 260000 SH Sole 260000 PepsiCo, Inc. COM 713448108 17175 250991 SH Sole 250991 Pfizer Inc. COM 717081103 18955 755808 SH Sole 755808 Platinum Underwriters Holdings COM G7127P100 18400 400000 SH Sole 400000 QUALCOMM Incorporated COM 747525103 43302 700000 SH Sole 700000 Republic Services, Inc. COM 760759100 28072 957100 SH Sole 957100 Royce Value Trust, Inc. COM 780910105 2198 163798 SH Sole 163798 Target Corporation COM 87612E106 27218 460000 SH Sole 460000 The ADT Corporation COM 00101J106 13598 292500 SH Sole 292500 The Manitowoc Company, Inc. COM 563571108 12936 825000 SH Sole 825000 The TJX Companies, Inc. COM 872540109 65571 1544668 SH Sole 1544668 Towers Watson & Co. Class A COM 891894107 14839 263998 SH Sole 263998 United Technologies Corporatio COM 913017109 26653 325000 SH Sole 325000 Universal Display Corporation COM 91347P105 994 38800 SH Sole 38800 Visteon Corporation COM 92839U206 17772 330211 SH Sole 330211 Vodafone Group plc ADR COM 92857W209 11917 473100 SH Sole 473100 Waste Management, Inc. COM 94106L109 21256 630000 SH Sole 630000 Weatherford International Ltd. COM H27013103 22940 2050000 SH Sole 2050000