UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F COVER PAGE Report for the Calendar Year or Quarter Ended: June 30, 2010 Check here if Amendment [ ]; Amendment Number: This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name:GENERAL AMERICAN INVESTORS COMPANY, INC. Address: 100 PARK AVE 35TH FLOOR NEW YORK, NY 10017 13F File Number: 28-461 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Eugene S. Stark Title: Vice-President, Administration Phone: 212-916-8447 Signature, Place, and Date of Signing: Eugene S. Stark New York, NY August 03, 2010 Report Type (Check only one.): [X] 13F HOLDINGS REPORT. [ ] 13F NOTICE. [ ] 13F COMBINATION REPORT. List of Other Managers Reporting for this Manager: Form 13F File Number Name I AM SIGNING THIS REPORT AS REQUIRED BY THE SECURITIES EXCHANGE ACT OF 1934. FORM 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 Form 13F Information Table Entry Total: 60 Form 13F Information Table Value Total: $836356357 List of Other Included Managers: No. 13F File Number Name VALUE SHARES/ SH/ PUT/ INVSTMT -----VOTING AUTHORITY----- NAME OF ISSUER -TITLE OF CLASS- --CUSIP-- x$1000 PRN AMT PRN CALL DSCRETN -MANAGERS- SOLE SHARED NONE COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8 ----------------- ---------- ---------- ---------- ---------- ---------- --------- ---------- Apple Inc. COMMON 037833100 15092 60000 SH SOLE 60000 0 0 ABB Ltd. ADR COMMON 000375204 20736 1200000 SH SOLE 1200000 0 0 Arch Capital Group Ltd. COMMON G0450A105 23468 315000 SH SOLE 315000 0 0 Adams Express Company COMMON 006212104 1163 128815 SH SOLE 128815 0 0 Alexander & Baldwin, Inc. COMMON 014482103 7031 236100 SH SOLE 236100 0 0 Amgen Inc. COMMON 031162100 2104 40000 SH SOLE 40000 0 0 Alpha Natural Resources, Inc. COMMON 02076X102 8948 264200 SH SOLE 264200 0 0 Apache Corporation COMMON 037411105 24876 295478 SH SOLE 295478 0 0 ASML Holding N.V. COMMON N07059186 19229 700000 SH SOLE 700000 0 0 American Express Company COMMON 025816109 12903 325000 SH SOLE 325000 0 0 Berkshire Hathaway Inc. Class A COMMON 084670108 13200 110 SH SOLE 110 0 0 Celgene Corporation COMMON 151020104 3049 60000 SH SOLE 60000 0 0 Cephalon, Inc. COMMON 156708109 21684 382100 SH SOLE 382100 0 0 Central Securities Corporation COMMON 155123102 652 35500 SH SOLE 35500 0 0 Canadian Natural Resources COMMON 136385101 8308 250000 SH SOLE 250000 0 0 Costco Wholesale Corporation COMMON 22160K105 31527 575000 SH SOLE 575000 0 0 Cisco Systems, Inc. COMMON 17275R102 20458 960000 SH SOLE 960000 0 0 CEMEX, S.A. de C.V. ADR COMMON 151290889 18826 1946880 SH SOLE 1946880 0 0 Cytokinetics, Incorporated COMMON 23282W100 1256 529900 SH SOLE 529900 0 0 Dell Inc. COMMON 24702R101 15557 1290000 SH SOLE 1290000 0 0 Diageo plc ADR COMMON 25243Q205 21959 350000 SH SOLE 350000 0 0 Devon Energy Corporation COMMON 25179M103 7923 130062 SH SOLE 130062 0 0 Epoch Holding Corporation COMMON 29428R103 20450 1666667 SH SOLE 1666667 0 0 Fidelity National Financial, Inc COMMON 31620R105 9743 750000 SH SOLE 750000 0 0 Gilead Sciences, Inc. COMMON 375558103 18665 544500 SH SOLE 544500 0 0 Halliburton Company COMMON 406216101 19640 800000 SH SOLE 800000 0 0 Hewitt Associates, Inc.Class A COMMON 42822Q100 16062 466100 SH SOLE 466100 0 0 International Game Technology COMMON 459902102 11775 750000 SH SOLE 750000 0 0 J.C. Penney Company, Inc. COMMON 708160106 8592 400000 SH SOLE 400000 0 0 JPMorgan Chase & Co. COMMON 46625H100 13729 375000 SH SOLE 375000 0 0 JPMorgan Chase & Co. COMMON 46634E114 1959 155000 SH SOLE 155000 0 0 Leap Wireless International, Inc COMMON 521863308 1012 78000 SH SOLE 78000 0 0 MetLife, Inc. COMMON 59156R108 10573 280000 SH SOLE 280000 0 0 MSCI Inc. Class A COMMON 55354G100 11097 405000 SH SOLE 405000 0 0 Microsoft Corporation COMMON 594918104 13116 570000 SH SOLE 570000 0 0 M&T Bank Corporation COMMON 55261F104 9769 115000 SH SOLE 115000 0 0 The Manitowoc Company, Inc. COMMON 563571108 5559 608198 SH SOLE 608198 0 0 Nelnet, Inc. COMMON 64031N108 11905 617500 SH SOLE 617500 0 0 NetEase.com, Inc. COMMON 64110W102 5330 168100 SH SOLE 168100 0 0 Nucor Corporation COMMON 670346105 5742 150000 SH SOLE 150000 0 0 Poniard Pharmaceuticals, Inc. COMMON 732449301 117 195344 SH SOLE 195344 0 0 PepsiCo, Inc. COMMON 713448108 18285 300000 SH SOLE 300000 0 0 Pfizer Inc. COMMON 717081103 10778 755808 SH SOLE 755808 0 0 PartnerRe Ltd. COMMON G6852T105 19289 275000 SH SOLE 275000 0 0 QUALCOMM Incorporated COMMON 747525103 22988 700000 SH SOLE 700000 0 0 Everest Re Group, Ltd. COMMON G3223R108 18387 260000 SH SOLE 260000 0 0 Republic Services, Inc. COMMON 760759100 28214 949000 SH SOLE 949000 0 0 Royce Value Trust, Inc. COMMON 780910105 1532 144955 SH SOLE 144955 0 0 Symetra Financial Corporation COMMON 87151Q106 2400 200000 SH SOLE 200000 0 0 Teradata Corporation COMMON 88076W103 13716 450000 SH SOLE 450000 0 0 The TJX Companies, Inc. COMMON 872540109 68479 1632400 SH SOLE 1632400 0 0 Transatlantic Holdings, Inc. COMMON 893521104 3981 83000 SH SOLE 83000 0 0 The Travelers Companies, Inc. COMMON 89417E109 9850 200000 SH SOLE 200000 0 0 Textron Inc. COMMON 883203101 3649 215000 SH SOLE 215000 0 0 United Technologies Corporation COMMON 913017109 21096 325000 SH SOLE 325000 0 0 Verifone Holdings, Inc. 1 3/8% NOTE 92342YAB5 9250 10000000 PRN SOLE 10000000 0 0 Weatherford International Ltd. COMMON G95089101 28251 2150000 SH SOLE 2150000 0 0 Waste Management, Inc. COMMON 94106L109 19713 630000 SH SOLE 630000 0 0 Wal-Mart Stores, Inc. COMMON 931142103 26439 550000 SH SOLE 550000 0 0 Xerox Corporation COMMON 984121103 15276 1900000 SH SOLE 1900000 0 0