UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ------------ FORM 6-K ------------ REPORT OF FOREIGN ISSUER Pursuant to Rule 13a-16 or 15d-16 of the Securities Exchange Act of 1934 FEBRUARY 5, 2008 ------------ NOVO NORDISK A/S (Exact name of Registrant as specified in its charter) NOVO ALLE DK-2880, BAGSVAERD DENMARK (Address of principal executive offices) ------------ Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F Form 20-F [X] Form 40-F [ ] Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934. Yes [ ] No [X] If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g-32(b):82-_____________________ DIRECTOR/PDMR SHAREHOLDING TRADING IN NOVO NORDISK SHARES BY BOARD MEMBERS, EXECUTIVES AND ASSOCIATED PERSONS AS REPORTED TO NOVO NORDISK ON 1 FEBRUARY 2008 In accordance with Section 28a of the Danish Securities Trading Act, Novo Nordisk is required on a daily basis to publish trading in Novo Nordisk shares by the company's board members, executives and their associated persons as reported by those persons to Novo Nordisk. As from 2004, members of Novo Nordisk's Executive Management and the other members of the Senior Management Board have participated in a performance-based incentive programme where a proportion of the calculated shareholder value creation has been allocated to a joint pool for the participants. For 2004, 252,688 shares were allocated to the joint pool and the market value of the scheme was expensed in the accounts for 2004. In accordance with the principles of the incentive programme, the Board of Directors of Novo Nordisk A/S on 30 January 2008 evaluated that the conditions for release of the joint pool of shares have been fulfilled. Accordingly, the shares in the joint pool were transferred to 22 current and former members of senior management on 31 January 2008. Please find below a statement of the transfer of shares to the members of Executive Management in accordance with the above and the subsequent trading in these shares by the members of Executive Management. NAME LARS REBIEN S0RENSEN REASON FOR REPORTING CHIEF EXECUTIVE OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION OTHER TRANSACTION (TRANSFER OF SHARES IN ACCORDANCE WITH LONG-TERM INCENTIVE PROGRAMME) DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 26,134 SHARES TOTAL VALUE OF TRANSACTION DKK 0 (TRANSFERRED IN ACCORDANCE WITH THE LONG-TERM INCENTIVE PROGRAMME FOR 2004) NAME LARS REBIEN S0RENSEN REASON FOR REPORTING CHIEF EXECUTIVE OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION SALE OF SHARES DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 26,134 SHARES TOTAL VALUE OF TRANSACTION DKK 8,131,855 NAME JESPER BRANDGAARD REASON FOR REPORTING CHIEF FINANCIAL OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION OTHER TRANSACTION (TRANSFER OF SHARES IN ACCORDANCE WITH LONG-TERM INCENTIVE PROGRAMME) DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 0 (TRANSFERRED IN ACCORDANCE WITH THE LONG-TERM INCENTIVE PROGRAMME FOR 2004) NAME JESPER BRANDGAARD REASON FOR REPORTING CHIEF FINANCIAL OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION SALE OF SHARES DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 5,422,274 NAME LISE KINGO REASON FOR REPORTING CHIEF OF STAFFS FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION OTHER TRANSACTION (TRANSFER OF SHARES IN ACCORDANCE WITH LONG-TERM INCENTIVE PROGRAMME) DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 0 (TRANSFERRED IN ACCORDANCE WITH THE LONG-TERM INCENTIVE PROGRAMME FOR 2004) NAME LISE KINGO REASON FOR REPORTING CHIEF OF STAFFS FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION SALE OF SHARES DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 5,422,274 NAME KARE SCHULTZ REASON FOR REPORTING CHIEF OPERATING OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION OTHER TRANSACTION (TRANSFER OF SHARES IN ACCORDANCE WITH LONG-TERM INCENTIVE PROGRAMME) DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 0 (TRANSFERRED IN ACCORDANCE WITH THE LONG-TERM INCENTIVE PROGRAMME FOR 2004) NAME MADS KROGSGAARD THOMSEN REASON FOR REPORTING CHIEF SCIENCE OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION OTHER TRANSACTION (TRANSFER OF SHARES IN ACCORDANCE WITH LONG-TERM INCENTIVE PROGRAMME) DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 0 (TRANSFERRED IN ACCORDANCE WITH THE LONG-TERM INCENTIVE PROGRAMME FOR 2004) NAME MADS KROGSGAARD THOMSEN REASON FOR REPORTING CHIEF SCIENCE OFFICER FINANCIAL INSTRUMENT AND ID CODE NOVO NORDISK B SHARES DK 006010261 TYPE OF TRANSACTION SALE OF SHARES DATE OF TRANSACTION 31 JANUARY 2008 PLACE OF TRANSACTION OMX THE NORDIC EXCHANGE COPENHAGEN VOLUME OF TRANSACTION 17,426 SHARES TOTAL VALUE OF TRANSACTION DKK 5,422,274 DEFINITIONS AND BACKGROUND INFORMATION: PUBLICATION Publication shall take place the day after Novo Nordisk receives sufficient information on the trading. Publication is only required when the total amount of transactions of a specific board member/executive and his/her associated persons in any one calendar year has reached 5,000 euros. WHO ARE BOARD MEMBERS, EXECUTIVES AND ASSOCIATED PERSONS? Board members and executives are members of the Board of Directors and Executive Management, respectively, of Novo Nordisk A/S. Associated persons are defined as the following persons associated to a board member/executive: 1) spouse or cohabitant, 2) children under the age of 18 years, 3) relatives defined as brothers, sisters, parents, grandparents etc, children, grandchildren etc who have shared the same household with a board member/executive for at least one year, and 4) any legal person, including a company, a foundation or a partnership, which is controlled directly or indirectly by a board member/executive and/or a person mentioned in 1)-3), or to which a board member/executive and/or a person mentioned in 1)-3) has managerial responsibilities or economic interests substantially equivalent to the legal person. WHAT IS TRADING/TRANSACTION? Trading is any kind of transaction, including shares purchased or otherwise acquired, shares sold or otherwise disposed, gifts, mortgages and grants and exercise of options, but not heritage. WHAT IS FINANCIAL INSTRUMENT AND ID CODE? Financial instrument includes shares listed on the OMX The Nordic Exchange Copenhagen and London Stock Exchange as well as ADRs listed on New York Stock Exchange, except for ADRs held in 401(k) retirement plan by US-based employees. The ID code is the code (ISIN DK006010261) of the Novo Nordisk share on OMX The Nordic Exchange Copenhagen, the code (NVOB) on London Stock Exchange or the code (NVO) on New York Stock Exchange. WHAT IS DATE AND PLACE OF TRANSACTION? Date of transaction is the actual transaction date. The place of transaction is the actual place of transaction, ie OMX The Nordic Exchange Copenhagen, London Stock Exchange or New York Stock Exchange. WHAT IS VOLUME AND VALUE OF TRANSACTION? The volume of transaction is the number of shares (of DKK 1 nominal value) or other financial instruments traded. The transaction value is the number of shares traded multiplied by the transaction price. The exchange rate of the Danish Central Bank (Nationalbanken) on the date of transaction is used for calculating the transaction value in DKK in case of shares traded on London Stock Exchange and ADRs listed on New York Stock Exchange. For further information please contact: Novo Nordisk is a healthcare company and a world leader in diabetes care. In addition, Novo Nordisk has a leading position within areas such as haemostasis management, growth hormone therapy and hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical products and services that make a significant difference to patients, the medical profession and society. With headquarters in Denmark, Novo Nordisk employs approximately 26,000 employees in 80 countries, and markets its products in 179 countries. Novo Nordisk's B shares are listed on the stock exchanges in Copenhagen and London. Its ADRs are listed on the New York Stock Exchange under the symbol 'NVO'. For more information, visit novonordisk.com. FOR FURTHER INFORMATION PLEASE CONTACT: Media: Investors: Outside North America: Outside North America: Elin K Hansen Mads Veggerby Lausten Tel: (+45) 4442 3450 Tel: (+45) 4443 7919 ekh@novonordisk.com mlau@novonordisk.com ------------------- -------------------- Hans Rommer Tel: (+45) 4442 4765 hrmm@novonordisk.com In North America: In North America: Sean Clements Christian Qvist Frandsen Tel: (+1) 609 514 8316 Tel: (+1) 609 919 7937 secl@novonordisk.com cqfr@novonordisk.com -------------------- -------------------- Stock Exchange Announcement no 4 / 2008 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf of the undersigned, thereunto duly authorized. Date: FEBRUARY 5, 2008 NOVO NORDISK A/S --------------------------------------------------- Lars Rebien Sorensen, President and Chief Executive Officer